當前位置:首頁 > 產(chǎn)品中心 > 抗體/抗原 > 標記一抗 > bs-5717R-HRPHRP標記的軸抑制蛋白2抗體
簡要描述:Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B.Involvement in disease:Defects in AXIN2 are involved in colorectal cancer (CRC). They appear to be specifically associated with defective mismatch repair.Defects in AXIN2 are the cause of oligodontia-colorectal cancer syndrome (ODCRCS). Affected individuals manifest severe tooth agenesis and colorectal cancer or precancerous lesions of variable type
詳細介紹
產(chǎn)品咨詢